منابع مشابه
Insulin receptors in virus-induced diabetes mellitus in mice.
Quantitative estimations were made of insulin receptors on liver cell membrane of DBA/2 mice infected with M variant of encephalomyocarditis virus. The virus produced an impairment of glucose metabolism on day 3 of infection, which lasted for 5 months. The fasting plasma insulin concentration was markedly decreased on day 14. The specific binding of 125-I insulin to the membrane receptor was si...
متن کاملVirus-induced diabetes mellitus. XX. Polyendocrinopathy and autoimmunity
Mice infected with reovirus type 1 developed transient diabetes and a runting syndrome. The diabetes was characterized by hyperglycemia, abnormal glucose tolerance tests, and hypoinsulinemia. Inflammatory cells and viral antigens were found in the islets of Langerhans, and virus particles were seen in alpha, beta, and delta cells. The runting syndrome consisted of retarded growth, oily hair, al...
متن کاملDiabetes Mellitus
دیابت بیماری متابولیکی است که بدلیل افزایش سطح گلوکز خون (هیپرگلیسمی) بدنبال بروز معایبی در ترشح انسولین، عملکرد انسولین یا هر دو عامل بروز می نماید.
متن کاملVirus-induced diabetes mellitus. XVIII. Inhibition by a nondiabetogenic variant of encephalomyocarditis virus
Plaque purification of the M variant of encephalomyocarditis (EMC) virus resulted in the isolation of two stable variants: one diabetogenic and designated D and the other nondiabetogenic and designated B. When the D variant was inoculated into SJL/J male mice, hypoinsulinemia and hyperglycemia developed in > 90% of the animals. In contrast, none of the mice inoculated with the B variant develop...
متن کاملtype 1 diabetes mellitus & gluten induced disorders
over the last five decades the association between coeliac disease and other autoimmune disorders such as autoimmune thyroid disease or diabetes mellitus type 1 has been well established through many studies and to this day is subject to on-going clinical and scientific investigation worldwide. while no link has been established between coeliac disease and type 2 diabetes mellitus, coeliac dise...
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ژورنال
عنوان ژورنال: Uirusu
سال: 1975
ISSN: 0042-6857,1884-3433
DOI: 10.2222/jsv.25.220